What are the Causes of Polycystic Kidney Disease(PKD)

Causes of Polycystic Kidney Disease(PKD)

Causes of Polycystic Kidney Disease(PKD)

Polycystic kidney disease is passed down through families , usually as an autosomal dominant trait. There are two different genetic flaws that lead to two types of PKD. PKD1, PKD2 and PKHD1 genes cause autosomal dominant polycystic kidney disease and autosomal recessive polycystic kidney disease.

Persons with PKD have many clusters of cysts in the kidneys. What exactly triggers the cysts to form is unknown.

Thear are som Risk factors:

Parental consanguinity

Presence of hepatic fibrosis

Siblings with PKD

As many as half of people with PKD have cysts on the liver. A family history of PKD increases your risk for the condition.In some cases, a person is with PKD without familial history of the disease. But this condition is rare to see.

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